The Problem of Alzheimer’s is a deeply researched, wide-ranging look at how what once may have been viewed as a rare and little-understood illness has become one of the defining medical and social crises of our time. Karlawish approaches the subject not just as a neurologist or scientist, but as a careful storyteller who traces the arc of the disease — from its first identification in the early 20th century, through decades of neglect and misunderstanding, to our present moment where Alzheimer’s affects millions and burdens countless families. (PublishersWeekly.com)
He blends history, science, and human stories: we go into research labs, meet patients and caregivers, and witness the struggle of families trying to preserve identity, dignity, and autonomy in the face of a disease that slowly erodes memory, decision-making, and selfhood. Karlawish argues that Alzheimer’s is not simply a medical or biological problem — it is also a humanitarian, political, and cultural challenge. He shows how health-care systems, public policy, economics, and social attitudes have all shaped the response to Alzheimer’s — and sometimes failed people living with it. (Macmillan Publishers)
Yet the book is not just a chronicle of despair. Amid the tragedy and heartbreak, Karlawish highlights scientific advances, evolving models of care, and social reforms that could — if taken seriously — provide better support for patients and caregivers. He invites readers to reconsider what “living with dementia” could mean: to think about autonomy, dignity, compassion, and how communities can adapt to offer more humane, thoughtful care. (Tradebooks for Courses)
In its ambition and empathy, The Problem of Alzheimer’s stands as more than a medical book. It is a call for awareness, understanding, and change — one that bridges science and humanity, history and policy, suffering and hope.
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